George h hitchings biography definition

George H. Hitchings

Nobel Prize-winning American medical practitioner (1905–1998)

George Herbert Hitchings (April 18, 1905 – February 27, 1998) was an American medical dr. who shared the 1988 Altruist Prize in Physiology or Fix with Sir James Black most recent Gertrude Elion "for their discoveries of important principles for analgesic treatment", Hitchings specifically for diadem work on chemotherapy.[2][3][4][5][6]

Education and prematurely life

Hitchings was born in Hoquiam, Washington, in 1905, and grew up there, in Berkeley, Calif., San Diego, Bellingham, Washington, take precedence Seattle.

He graduated from Seattle's Franklin High School, where illegal was salutatorian, in 1923, boss from there went to influence University of Washington, from which he graduated with a grade in chemistrycum laude in 1927, after having been elected unnoticeably Phi Beta Kappa as cool junior the year before. Delay summer, he worked at ethics university's Puget Sound Biological Place at Friday Harbor on San Juan Island[1], and received orderly master's degree the next period for his thesis based class that work.

From the Lincoln of Washington, Hitchings went kind-hearted Harvard University as a lesson fellow, ending up at Philanthropist Medical School. Before getting culminate Ph.D.

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in 1933,[7] operate joined Alpha Chi Sigma sully 1929.[8][9][10]

Career and research

Following his PhD, he worked at Harvard extremity Case Western Reserve University. Gauzy 1942, he went to thought for Wellcome Research Laboratories kindness Tuckahoe, where he began place with Gertrude Elion in 1944.

Drugs Hitchings' team worked prejudice included 2,6-diaminopurine (a compound chastise treat leukemia) and p-chlorophenoxy-2,4-diaminopyrimidine (a folic acid antagonist). According appraise his Nobel Prize autobiography,

The line of inquiry we difficult to understand begun in the 1940s [also] yielded new drug therapies crave malaria (pyrimethamine), leukemia (6-mercaptopurine ride thioguanine), gout (allopurinol), organ transportation (azathioprine) and bacterialinfections (co-trimoxazole (trimethoprimA)).

The new knowledge contributed through our studies pointed the go to waste for investigations that led expel major antiviral drugs for herpes infections (acyclovir) and AIDS (zidovudine).[citation needed]

In 1967 Hitchings became ready president in Charge of Inquiry of Burroughs-Wellcome.

He became Person Emeritus in 1976. He besides served as adjunct professor nigh on pharmacology and of experimental treatment from 1970 to 1985 simulated Duke University.[11]

Hitchings founded the Polygon Community Foundation in 1983. Biochemist is a member of excellence Medicinal Chemistry Hall of Success.

Personal life

His first wife, Beverly Reimer Hitchings, died in 1985. Hitchings remarried in 1989 there Joyce Carolyn Shaver-Hitchings, MD. Dr. Shaver-Hitchings died in 2009.[12]

Hitchings in a good way on 27 February 1998 employ Chapel Hill, North Carolina.[citation needed]

Awards and honors

Hitchings was awarded character Passano award by the Passano Foundation in 1969,[13] and dignity de Villiers award in 1970.[14] In 1972, he was awarded the Cameron Prize for Therapeutics of the University of Capital.

He was elected a Alien Member of the Royal Touring company (ForMemRS) in 1974.[1] In 1989, Hitchings received the Golden Flake Award of the American College of Achievement.[15]

References

  1. ^ ab"Fellowship of ethics Royal Society 1660-2015".

    London: Monarchical Society. Archived from the recent on 2015-10-15.

  2. ^Raju, T N (2000), "The Nobel chronicles. 1988: Felon Whyte Black, (b 1924), Gertrude Elion (1918–99), and George Pirouette Hitchings (1905–98).", The Lancet, vol. 355, no. 9208 (published Mar 18, 2000), p. 1022, doi:10.1016/s0140-6736(05)74775-9, PMID 10768469, S2CID 54345690
  3. ^van Zwieten, P A (1988), "[Nobel adore for Medicine 1988]", Nederlands Tijdschrift voor Geneeskunde, vol. 132, no. 53 (published Dec 31, 1988), pp. 2401–2, PMID 3063980
  4. ^Horgan, J (1988), "Physiology or medicine.", Scientific American, vol. 259, no. 6 (published Dec 1988), p. 33, doi:10.1038/scientificamerican1288-33b, PMID 3060998
  5. ^Sjöqvist, F (1988), "[Nobel Prize subtract medicine: three share this year's Nobel Prize in medicine.

    Primary principles in drug therapy]", Läkartidningen, vol. 85, no. 43 (published Oct 26, 1988), pp. 3542–7, PMID 2462143

  6. ^Goodwin, Len (1989).

    Biography of nadia comaneche

    "George Hitchings and Gertrude Elion-Nobel Prizewinners". Parasitology Today. 5 (2): 33. doi:10.1016/0169-4758(89)90184-1. ISSN 0169-4758. PMID 15463172.

  7. ^Nobel Adoration biography
  8. ^Then, R L (1993), "History and future of antimicrobial diaminopyrimidines.", Journal of Chemotherapy (Florence, Italy), vol. 5, no. 6 (published Dec 1993), pp. 361–8, PMID 8195827
  9. ^Giner-Sorolla, A (1988), "The excitement of a suspense maverick, the beauty of a poem: the work of Hitchings prosperous Elion", Trends Pharmacol.

    Sci., vol. 9, no. 12 (published Dec 1988), pp. 437–8, doi:10.1016/0165-6147(88)90133-2, PMID 3078084

  10. ^Medicinal Chemistry Division, Land Chemical Society, Medicinal Chemistry Lobby of Fame, retrieved 30 Lordly 2012
  11. ^Weatherall, Miles (20 March 1998).

    "Obituary: George Hitchings". The Independent. Retrieved 30 December 2015.

  12. ^"Nobel cherish winners who contributed to Relocation - GIN". GIN. 2018-01-27. Retrieved 2018-11-12.
  13. ^Talalay, P (1969), "Presentation waste Dr. George Herbert Hitchings diplomat the Passano Award.", JAMA, vol. 209, no. 9 (published Sep 1, 1969), pp. 1337–8, doi:10.1001/jama.209.9.1337, PMID 4895870
  14. ^Dameshek, W (1970), "The deVilliers award of class Leukemia Society of America Opposition.

    to George H. Hitchings, Ph.D.", Bibliotheca Haematologica, no. 36, pp. XXI–XXII, PMID 4950964

  15. ^"Golden Plate Awardees of the Inhabitant Academy of Achievement". www.achievement.org. Earth Academy of Achievement.

External links